Development of a Composite Measure of the Nasal Airway
Sleep Apnea Research Group
Principal Investigator: Derek J. Lam, MD
Co-Principal Investigator: Edward M. Weaver, MD, MPH
Co-Investigators: Kathryn T. James, PA, MPH
American Journal of Rhinology (in press)
Background – Studies comparing different categories of nasal measures have reported inconsistent results. We sought to compare validated measures of the nasal airway: anatomic (acoustic rhinometry), physiologic (nasal peak inspiratory flow), and subjective experience (Nasal Obstruction Symptom Evaluation Scale and a visual analog scale).
Methods – This prospective cross-sectional study of 290 non-rhinologic patients included upright and supine rhinometry (minimum cross sectional area and volume) and flow (mean and maximum) measurerments, as well as subjective measures. Associations between measures were evaluated with Spearman correlations and multivariate linear regression, adjusting for age, sex, race, body mass index, and smoking history.
Results – Correlations between objective (rhinometry and flow) and subjective categories of nasal measures ranged from -0.16 to 0.03 (mean correlation -0.07
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